What did Columbus want to do? In the 15th and 16th centuries, Europeans wanted to find sea routes to the Far East. Columbus wanted to find a new route to India, China, Japan and the Spice Islands. If he could reach these lands, he would be able to bring back rich cargoes of silks and spices.
Over the period of the Atlantic Slave Trade, from approximately 1526 to 1867, some 12.5 million slaves were shipped from Africa, and 10.7 million arrived in the Americas.
Manifest destiny affected native americans' lives because the white colonized men who believed they should move west and spread their religion forced indian americans to leave their land and claim it as theirs.