Answer: The answer is D: to allow maximum exposure to light and to reduce shading of lower leaves.
Explanation:
The arrangement of leaves on a Stem is known as Phyllotaxy. It is used to enable them obtain maximum exposure to sunlight.
Leaves are classified as either alternate, spiral or opposite.
Leaves with alternate pattern arise at a different point (node) on the stem. This helps reduce shading of the lower leaves.
Paleobotany is the study of plant fossils and remains. This can help us understand how plants lived long ago and how they were like.
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Answer:
20%
Explanation:
A species is placed on the endangered species list when its overall population sees a reduction of 20% over a 10 year period or a 3 generation period.
(This is correct, because I got it right on my quiz)
Mosunetuzumab is a T-cell reliant bispecific antibody that binds to CD3 and CD20 to trigger T-cell mediated B-cell death.
However, cytokine release syndrome, which has the potential to limit dose and efficacy, can result from powerful immune stimulation with T-cell focused treatments.
We created a novel mechanistic model of immune and antitumor responses to the T-cell bispecifics (mosunetuzumab and blinatumomab), taking into account the dynamics of B- and T-lymphocytes in circulation, lymphoid tissues, and tumors, in order to better understand the mechanisms underlying safety and efficacy as well as to explore safety mitigation strategies.
Using mosunetuzumab nonclinical and blinatumomab clinical data, the model was created and validated. The initial step-fractionated dose was projected to minimize systemic T-cell activation and cytokine release without impairing tumour response.
Simulations described the mechanisms underlying the observed cell and cytokine (IL6) dynamics. The Phase I clinical study for mosunetuzumab was changed to a step-fractionated treatment schedule as a result of these findings, allowing for the safer administration of greater dosages.
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