Answer: If a mutation occurred in Silencer of Death Domain (SODD) that prohibited its interaction with the DD of TNF receptor, the TNF receptor would evoke its response by binding to a transmembrane receptor, TNFR1.
Explanation: Binding to TNFR1 inhibits the recruitment of cytoplasmic signaling proteins to TNFR1 to prevent recruitment of a number of protein (TRADD) or prevent spontaneous aggregation of the cytoplasmic death domains of TNFR1 molecules.
SODD mechanism is useful in preventing unwarranted TNFR1 activation in the process of apoptosis.
Answer:
"Action potential is a rapid rise and subsequent fall in voltage or membrane potential across a cellular membrane with a characteristic pattern."
It is the mode through which a neuron transports electrical signals.
Explanation:
- Option - (a) is the best choice to choose from,
- <u>The refractory period :</u>
A second action potential cannot occur until the membrane has recovered or reestablished, this is the refractory period. The absolute refractory period coincides with inactivation of voltage-gated sodium channels which makes it impossible to generate another nerve impulse.
The Renaissance Europe differ from medieval Europe is by Populations shifted from cities to small towns and rural villages.
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