The Powhatan Confederacy were the native people of Virginia.They did not have a good relationship with the British settlers at the very start because the British thought the natives would provide their food.
In my opinion, the most important similarity between these two men is that they are both democrats. They both believe in the common people rather than in elites.
Jefferson was the leader of the Democratic-Republicans. This was the party that wanted more power for the common people. They wanted there to be less hierarchy in American society. They wanted America to be dominated by small farmers.
Jackson also favored the common people. He wanted to do things like destroying the Bank of the United States because he felt that it favored the rich over the common people.
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Because plantation owners were mainly in the southern states. Also because there were many people that bought them from the south than anywhere else :)
The leader of the Department of State is the Secretary of State and the first Secretary of State was future President Thomas Jefferson who held the role from 1790-1793.
Jefferson's time as Secretary of State was marked by an intense rivalry with Secretary of the Treasury Alexander Hamilton and a growing divide between the parties in the capital.