The correct answer is option 3. "secondary structure".
Explanation:
The secondary structure of polypeptide and proteins refers to the second order of folding, including common structures such as beta sheets, alpha helix, as well as turns and loops. The hydrogen bonds between the oxygen and nitrogen atoms of the peptide bonds are crucial to secondary structures, as these hydrogen bonds form and stabilize the aforementioned common structures.
Well, (not trying to plagiarize) the client is expressing their fear of surgery, and this is from the body's reaction to danger (emotionally and physically).