Obesity can be defined as a condition in which there is overabundance of fat in the body and has pile up to a level that it is capable of causing a detrimental effect on health.
Secondary obesity is a medical condition that has caused an individual to be overweight. This disease can be caused by Cushing's disease, hypothalamic obesity disorders and some congenital conditions.
When Cushing's diseases occurs, the pituiary gland(an organ in the endocrine system) is triggered to release excess hormone (specifically excess adrenocorticotropic hormone). Some of the noticeable Symptoms of Cushing's diseases includes; Fatty depots begins to accumulate in the neck region, protrude belly as a result of weight gain around the mid section and loss of fat from the both hands and legs, sometimes purple or pink stretch mark are seen.
skin appendages can redirect and or stop the absorption of the drug as well as the physio-chemical properties of the drug itself that make it harder for the skin to absorb
