The theme is the main idea, what the passage was all about. The "big idea".
Answer:
the spelling error in this sentence is meddle she did not want them to meddle in her buissness not medal as in you won a award
Explanation:
The answer is B. Given this.
Signal words (also called transitions) help connect ideas inside the structure of a text. There are many types of signal words, for instance: comparison words, contrast words, emphasis words and so on.
In the excerpt asked about, we have the expression "given this", which connects the idea that is about to be developed with the ideas and arguments that have already been pointed out in the previous paragraphs. This is expression signals a relationship of cause and effect. Given ... circumstances, we have... results.
OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
Maggie is shy and doesn't have much confidence at this point of the story.
