Question

There is good evidence in some species that testosterone does not masculinize the brain directly, that it is first converted to estradiol, which then masculinizes the brain. This hypothesis is called the __________ hypothesis.

Answer 1

Answer:

The correct answer will be- Aromatization hypothesis

Explanation:

Traditionally it was believed that giving testosterone to the human makes the brain masculine and its effect depends on the estrogen receptors.

The testosterone hormone (androgen) produced from the testis enters the brain which there gets converted to  17-β estradiol (E2) by aromatase enzyme which acts on the estrogen receptors and develops the rodent brain.

Since the pathway involves the enzyme aromatase, therefore, aromatization hypothesis is the correct answer.