French King Phillip IV moved Pope to Avignon, which caused a weaker church.
A. Global economies suffered. Tariffs were high. Unequal distribution of wealth - caused people to not have money or jobs to buy items needed to keep the economy going. Length and severity of Great Depression went far beyond the normal rhythms of the business cycle. Availability of easy credit. Buying on speculation - buying and selling quickly for profit; caused prices to be "inflated". Investors used margin buying - purchasing stocks with borrowed money.
B. Use money that you already have to buy stock and don't just buy stock to make a quick dollar.
Gunpowder in Tang and moveable wooden type in Song.
Essentially the Scientific Revolution contributed to the progress, reason, andfraternal aspects of the Enlightenment. Through debunking long held superstitious / religious beliefs, producing a secular body of reasoned work, and by creating a network of learned fraternal Scientific Societies, who not only collaborated in theoretical fields, but in the application of new discoveries to practical and commercial purposes, along with offering libraries of the latest Scientific papers and lecturers. Enabling and funding further investigation, in a meritocratic circle eg. the Lunar Society of Birmingham.
Worth noting, the Agricultural revolution, which was applying scientific method to food production, was also vital as its gains freed manpower for the new urban mines and factories.