Answer:
5.5|1/4
Explanation:
.... ..... ........ .........
Answer:
The correct answer is- 4:0
Explanation:
Marfan syndrome is a genetic problem which affects the connective tissue in the body. The trait for this disease is autosomal dominant which means even one abnormal copy of this gene in the offspring or individual is sufficient to cause this syndrome.
Let S is the allele that is dominant for this syndrome and s is recessive. So if a cross between homozygous dominant(SS) and heterozygous individual (Ss) occurs than all the offspring would have this syndrome.
S s
S SS Ss
S SS Ss
Therefore all 4 offspring would have at least one dominant allele which is sufficient to cause this syndrome. So the phenotype ratio would be 4:0.
Answer:
The correct answer is "5-1-3-2-4".
Explanation:
Internalization of LDL particles into cells, is needed to form the intracellular vesicles known as endosomes. The order of events that allow for this process are:
5) LDL receptors migrate to the cell surface and cluster in clathrin-coated pits. Clathrin acts directing the receptors to the cell membrane region where endosomes are formed.
1) A combination of cholesterol and apolipoprotein binds to LDL receptors and becomes internalized as endocytotic vesicles. Once the receptors are in the proper cell membrane region, cholesterol and apolipoprotein are bound and internalized.
3) Several endocytotic vesicles fuse to form an endosome.
2) The environment of the endosome becomes acidic, which causes the LDL to dissociate from its receptor; additionally, the endosome fuses with a lysosome. LDL should be dissociated from its receptor since it is going to be degraded in the following step.
4) The LDL particle is degraded by the lysosome. This takes place after endocytosis, when LDL particles are transported into lysosomes once they are fused, cleaving the cholesterol esters into cholesterol and fatty acids.
