Answer:
Disease. When the Spanish arrived, they brought with them smallpox. Smallpox spread among the indigenous people and crippled their ability to resist the Spanish. The disease devastated the Aztec people, greatly reducing their population and killing an estimated half of Tenochtitlan's inhabitants.
Explanation:
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22 is the third choice. 23 should be the second option. I don’t know the first one.
One of the main factors leading up to the Civil War was territorial expansion into places like Arizona and Texas, with the question being whether these new states would be free or slave. It was in Arizona's interest to side with the slave states.