Exuse me, but I don't understand what you are saying. Are you referring to another question you posted? I really want to help you but I don't understand your question.
Answer:
B
Explanation:
This sentence can be written as in B, or it can be written without a comma by changing the structure and word choice. Commas are used to mark pauses so that the emphasis of the sentence is clear and so that the interrupters have the desired effect.
Another way to write this sentence would be:
There really is no way to know in advance.
Probably not but no one really knows 1000% because there isn't any evidence to back it up
