The slowest drug absorption/response is definitely oral/digestion route.
The fastest drug response time route would be intravenous, the drugs directly enter the blood so it can work instantly. Snorting/inhaling drug still need time to be absorbed to the blood vessel. It might be fast enough if used for local response (example: asthma). The mechanism probably by mucosa diffusion so its similar to rectal or sublingual route.
Capillaries are generally arranged in masses known as capillary beds. The number of capillaries in a capillary bed depends on the tissue of organ supplied.
Because women usually have a BMI lower than men causing the alcohol to affect the body more because of the BMI difference. also, women absorb the chemicals in alcohol faster because of the estrogen.
It is called paradox obesity
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