The answer is C, i just did it and got it right so you can trust this answer, i wrote so much because of the 20 character thing
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<span>The ecosystem is the lowest level of the biosphere hierarchy to include weather patterns and soil conditions.
in the whole biosphere hierarchy, ecosystem actually placed as the second highest (1 place below biosphere)
But there are only 2 hierarchy that include weather and soils, and those hierarchies are biosphere and ecosystem. So technically the ecosystem will be the lowest in this matter</span>
Ans.
The first pass effect is defined as a phenomenon of metabolism of drug, in which drug concentration is greatly decreased before reaching the systemic circulation. It represents that fraction of drug lost, at the time of absorption of drug in gut.
Thus, the client is not receiving all the dosage of ingested drug (aspirin) because of the 'first pass effect.'