Answer:
The important role of the functions of various domains of the fibronectin molecule or the laminin molecule are-
Fibronectin
-It can bind to fibrin which is important in blood clotting, and fibronectin can attach to heparin sulfate proteoglycans or collagen for binding it to the Extra Cellular Matrix.
-The RDG-containing cell-binding domain of fibronectin is very important for permitting cells to bind to this molecule, due to the fact that it is site that is attach by integrins on the surface of the cell.
Laminin
-A collagen IV binding site permits it to bind to the basal laminae (the molecule is predominantly found at this site).
-_6_1 integrins specific integral-binding site
Both Fibronectin and Laminin
-allow to attach to other ECM proteins.
