Although many of the Founding Fathers acknowledged that slavery violated the core American Revolutionary ideal of liberty, their simultaneous commitment to private property rights, principles of limited government, and intersectional harmony prevented them from making a bold move against slavery. The considerable investment of Southern Founders in slave-based staple agriculture, combined with their deep-seated racial prejudice, posed additional obstacles to emancipation.
Americans like William Lloyd Garrison and Frederick Douglass were some of the driving forces behind the anti-slavery movement.
I would be hard to argue that the Renaissance even impacted everyone directly.
The best answer to this is that the Renaissance created a period of social and economic upheaval that changed people's lives. Change is not always good and people were uprooted and put into new situations as a result.
