Answer:
The impact was most severe in the Caribbean, where by 1600 Native American populations on most islands had plummeted by more than 99 percent. Across the Americas, populations fell by 50 percent to 95 percent by 1650. The disease component of the Columbian Exchange was decidedly one-sided.
An indentured servant was someone who would pay for his journey to the US or for his debt by serving the person who helped him and after a while the debt would be over and the person would be free. The person would have all rights like regular people. Slaves had no rights at all and were not even observed as people and their slavery would never end unless the owner specifically freed them. Slavery was not contractual unlike indentured serviture.
"Ulysses S. Grant became a colonel in the Union volunteer army. His first victory was when he captured Fort Henry and Fort Donelson in February 1862. Also this man opened two rivers, and received national recognition for victories in February 1862, the first major Union victories of the war."