Answer:
You are a family physician and you have several patients that are coming in to have their moles looked at for possible melanoma.For each of the following patients use the ABCD chart to identify whether their moles are suspicious for melanoma.In the box below each mole image write a summary paragraph answering the following:1.Is there a possibility the mole is cancerous and why/why not?2.What is your advice to the patient for this mole? (none, proper sun care, removal, etc.)The diameter is too big and the color variation is different he just is unlucky because he may have skin cancer. The border is bad and its asymmetrical. Must see doctor.Patient 3 InformationPatient is 30 yr. old Native American female with medium skin tone with no history of skin cancer.She has had very little sun exposure and it is located on the medial side of her right knee and is 14 mm.The mole border looks pretty good, and the color is consistent.But due to his family’s history he should really get checked out and have an infinite amount of sunscreen on when he is outside.Plus the diameter is smaller than a pencil’s eraser which is 6mm.Patient 2 InformationPatient is 10 yr.old Caucasian male with very fair skin who has no history of skin cancer, but every member of his family has.He has had average sun exposure and it is located 3 inches distal of his left elbow and is 4 mm.The mole may be cancerous because she has already had 3melanomas removed. The mole looks like it varies in color, the border is all over the place and it’s not symmetrical. She also confesses to being at the beach all the time. My advice would be to get a full evaluation done and to stay out of the sun.Patient 1 InformationPatient is a 73 yr.old Caucasian female with fair skin who has had 3 melanomas removed in the past 2 years.She is a self-confessed beach bum and has been since 1950.It is located on her right shoulder and 6 mm.
Changes in a gene will change the form of the protein that it produces which in turn changes it's function
This is a type III hypersensitivity reaction mediated by immune complex deposits. Immune complexes are antigen-antibody (commonly IgG) complexes that are soluble and prone to deposition in multiple organs. Once immune complexes are deposited in an organ, neutrophils and macrophages will then attack the organ causing organ damage and eventually failure. Type III hypersensitivity reactions are characteristic in SLE and other autoimmune diseases such as rheumatoid arthritis, etc.
Other types are type I hypersensitivity which are mediated by mast cells and histamine with the involvement of IgE and this commonly happens in allergic reactions. Type II hypersensitivity is cytotoxic hypersensitivity wherein antibodies directly attack organs (not forming immune complexes). Type IV hypersensitivity (or cell-mediated toxicity) involves T-lymphocytes. This is a delayed type of hypersensitivity exemplified by reactions from <em>M. tuberculosis</em> bacilli in tuberculous disease.
DNA sequence can be altered by the process called as mutation. Mutation of DNA sequence can have a positive or negative effect on an organism and it entirely depends on the point and type of mutation that has occurred on the DNA sequences.
Mutations can be point mutation where single nucleotide base gets altered or deletion where a base pair gets deleted from the DNA sequences and many more. Mutation has driven the evolution of the organism.
This is simply because U.S is a large country with vastly different landscapes. New England states in the North, have rough winters so weather stations are built to depict the most accurate estimate of the freezing temperatures. Southern states in the South have rough summers and high levels of humidity so stations are built to depict those numbers.