The binding of chemical messengers to receptors often results in a shape change, which affects receptor function.
Explanation:
Binding of specific chemical messengers to the corresponding receptors of target cells brings about change in the shape of the receptors. This structural change in the receptor results in the generation of the desired response.It reflects how the form and specific configuration of substances or biomolecules affect their functions.
For example, binding of neurotransmitters to the receptors present on neurons opens the associated ligand-gated ion channels to allow the movement of specific ions through it. In the absence of bound ligand, these channels are present in a closed conformation.
