Red blood cells do not pop in the bloodstream because of the osmosis, a specialized case of diffusion . Osmosis is the movement of <span>water through a selectively permeable membrane from a region of its higher concentration to a region of its lower concentration.</span>
Oncogenes are most like the gas pedal on a car, while tumor suppressor genes are most like the brakes on a car. Oncogenes and tumor suppressor genes are mutated in cancer cells.
Oncogenes are genes overexpressed in cells in which they should not be expressed, thereby leading to cancer.
Some examples of oncogenes are growth factors such as, for example, the Platelet-derived growth factor (PDGF) or Epidermal growth factor (EGF).
Conversely, tumor suppressor genes are genes that act to regulate cell division and replication, thereby their inactivation also leads to cancer.
A well-known example of a tumor suppressor gene is the p53 gene that acts to control cell division and apoptosis (programmed cell death).
Learn more in:
brainly.com/question/14662375
C. Since they have to gain that skill.
<span>Rhabdomyolysis constitutes a common cause of acute renal failure and presents paramount interest. A large variety of causes with different pathogenetic mechanisms can involve skeletal muscles resulting in rhabdomyolysis with or without acute renal failure. Crush syndrome, one of the most common causes of rhabdomyolysis presents increased clinical interest, particularly in areas often involved by earthquakes, such as Greece and Turkey. Drug abusers are another sensitive group of young patients prone to rhabdomyolysis, which attracts the clinical interest of a variety of medical specialties.
We herein review the evidence extracted from updated literature concerning the data related to pathogenetic mechanisms and pathophysiology as well as the management of this interesting syndrome.
Keywords: Rhabdomyolysis, acute renal failure, myoglobin, crush syndrome
The first case of the crush syndrome, which constitutes one of the main causes of rhabdomyolysis, was reported in Sicily in 1908, after an earthquake1,2. In 1930, in the Baltic area, an epidemic of myoglobinuria was observed due to consumption of contaminated fish. Interest in rhabdomyolysis and crash syndrome was stimulated during the World War II particularly after the bombing in London, where the victims developed acute renal failure and myoglobinuria1.
Rhabdomyolysis is a rupture (lysis) of skeletal muscles due to drugs, toxins, inherited disorders, infections, trauma and compression3. Lysis of muscle cells releases toxic intracellular components in the systemic circulation which leads to electrolyte disturbances, hypovolemia, metabolic acidocis, coagulation defects and acute renal failure due to myoglobin4.
The skeletal muscle consists of cylindrical myofibrils, which contain variant structural and contraction proteins. Actin and myosin, arranged in thin and thick filaments respectively, form the repeated functional units of contraction, the sarcomeres5. The sarcoplasmic reticulum constitutes an important cellular calcium storage. It is structurally connected to the t-tubules, that are formed by invaginations of the muscle cell plasma membrane, the sarcelemma, around every fibril (Figure 1). After the sarcelemma depolarization, the stimulation arrives, through the t-tubules junctions, at the sarcoplasmic reticulum, inducing the calcium ions release and triggering muscle contraction6.</span>
