Explanation:
The pathophysiology underlying acne is described by the contribution of many factors such as changes in follicular growth, interaction with Propionibacterium acnes in the follicles, an immune and inflammatory response.
Topical and oral antibiotics are used to provide antibacterial actions, but they also serve as anti-inflammatories that inhibit macrophages and neutrophils and with this the cytokine production reducing the local inflammatory response.
Therefore, sometimes acne is treated with an antibiotic because it has antibacterial and anti-inflammatory effects.
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