Tension force is an example of a contact force<br><br> true or false

Describe the substrate specificity of chymotrypsin and the structural feature that determines this specificity.

serg [7]

Answer:

The main substrate of chymotrypsin includes tryptophan, tyrosine, phenylalanine and methionine

Explanation:

1.

Histidine yields a proton to aspartate and recovers it from serine.

Seen in another way: aspartate captures a proton from the serine through histidine.

2.

a) The serine (deprotonated) is thus capable of attacking the peptide bond (nucleophilic carbonyl attack) and forms a tetrahedral intermediate; The substrate is thus covalently bound to the enzyme (now it is a transition state).

b) The peptide bond is broken and the released amino terminus (R) recovers a proton from histidine.

c) Histidine, in turn, recovers it from aspartic.

3.

a) Aspartate captures a proton of histidine again, so that it can capture it in turn from water.

b) This generates a hydroxide anion that attacks the ester intermediate between the serine and the carboxyl part (R ′) of the substrate peptide.

c) A new tetrahedral intermediate bound to the enzyme is formed (via serine residue).

4.

a) The carboxyl group of the peptide is regenerated, the serine being separated and the other peptide fragment being free (the R ′ part with a free carboxyl end)

b) The serine recovers the proton at the expense of histidine, which in turn captures it from aspartic acid.

c) The catalytic triad (Asp, His, Ser) has been regenerated in its original state.

The net reaction is:

R–NH – CO –R ′ + H2O ⟶ R– NH2 + HOOC –R ′ ⟶ R – NH3 + + −OOC –R ′

The active site or catalytic center of chymotrypsin is formed by several amino acid residues, among which the essential role corresponds to the "catalytic triad".

5 0

4 years ago

Which describes John datiton observations of elements in any given compound

dmitriy555 [2]

Atoms of different elements always combine in the same way.

John Dalton noted that if the components are added to one exacerbated, the share of their masses will dependably be the same. Dalton's been an English scholar. The component mass of that mix is measured by the confirmation of the presence of molecules assembled by John Dalton.

3 0

3 years ago

Where do elctrons get their energy in photosytem I

Afina-wow [57]

Answer:

When light energy is absorbed by a chlorophyll molecule its electrons gain energy and move to higher energy levels in the molecule

5 0

3 years ago

How do you think the sum of their temperatures would change over time? Explain

Blizzard [7]

Answer: What is their?

Explanation: Explain?

7 0

3 years ago

Which of the following statements best describes the role of hormones in the body? Hormones send chemical signals throughout the

il63 [147K]

Answer:

Hormone production and release are primarily controlled by negative feedback. In negative feedback systems, a stimulus elicits the release of a substance; once the substance reaches a certain level, it sends a signal that stops further release of the substance. In this way, the concentration of hormones in blood is maintained within a narrow range. For example, the anterior pituitary signals the thyroid to release thyroid hormones. Increasing levels of these hormones in the blood then give feedback to the hypothalamus and anterior pituitary to inhibit further signaling to the thyroid gland, as illustrated in Figure 18.14. There are three mechanisms by which endocrine glands are stimulated to synthesize and release hormones: humoral stimuli, hormonal stimuli, and neural stimuli.

Explanation:

Hyperthyroidism is a condition in which the thyroid gland is overactive. Hypothyroidism is a condition in which the thyroid gland is underactive. Which of the conditions are the following two patients most likely to have?

Patient A has symptoms including weight gain, cold sensitivity, low heart rate and fatigue.

Patient B has symptoms including weight loss, profuse sweating, increased heart rate and difficulty sleeping.Humoral Stimuli

The term “humoral” is derived from the term “humor,” which refers to bodily fluids such as blood. A humoral stimulus refers to the control of hormone release in response to changes in extracellular fluids such as blood or the ion concentration in the blood. For example, a rise in blood glucose levels triggers the pancreatic release of insulin. Insulin causes blood glucose levels to drop, which signals the pancreas to stop producing insulin in a negative feedback loop.

Hormonal stimuli refers to the release of a hormone in response to another hormone. A number of endocrine glands release hormones when stimulated by hormones released by other endocrine glands. For example, the hypothalamus produces hormones that stimulate the anterior portion of the pituitary gland. The anterior pituitary in turn releases hormones that regulate hormone production by other endocrine glands. The anterior pituitary releases the thyroid-stimulating hormone, which then stimulates the thyroid gland to produce the hormones T3 and T4. As blood concentrations of T3 and T4 rise, they inhibit both the pituitary and the hypothalamus in a negative feedback loop.

3 0

3 years ago

Tension force is an example of a contact force true or false