Answer: The solvents break all noncovalent interactions
Explanation: Non-covalent interactions, i.e. bonds in proteins, are necessary because such bonds allow the binding of large molecules such as proteins. In order for a scientist to study how proteins fold, he must break all noncovalent interactions, and does so with the help of solvents. The protein is denatured by the solvent, and the scientist observes, i.e. studies the process of refolding.