The most impactful changes to Native American populations done by the colonial settlement was:
1 - the disease - smallpox and influenza killed almost 90% American Native population 2. extermination policies - by hunting them, the population was in decline3. Territory - the colonists took their land4. forced relocation policies - the colonits forced them to stay in some special place, no leaving, starving them5. coexistence reasoning - the differences between colonist and Native believes
The programs focused on what historians refer to as the "3 Rs": relief for the unemployed and poor, recovery of the economy back to normal levels, and reform of the financial system to prevent a repeat depression
I hope this helps you with what you are looking for.
The Missouri Compromise of 1820 involved land gained from the Louisiana Purchase. The Louisiana Purchase was the purchase of land from France in 1803 that consisted of over 530 million acres.
