Answer:
Hi!
The answer is (C) Both (a) and (b)
Explanation:
Drug Metabolism:
- Drug metabolism is divided into two steps: Phase 1 and Phase 2 reactions.
- Phase 1 reactions involve the degradation or formation of functional groups.
- Phase 2 reactions involve the conjugation of the drug or its Phase 1 intermediate with a polar conjugating molecule. Phase 2 generally performs the detoxification step in the drug degradation process.
- Phase 2 or conjugation reactions are further divided into 2 types:
- Type 1: Glucoronidation and sulfonation: An activated conjugating molecule such as glucoronic acid, sulfate or glutathione etc. is combined with the drug to form a conjugated molecule.
- Type 2: Amino acid conjugation: An activated drug or substrate is conjugated with an amino acid such as glycine or glutamine.
Glutathione Conjugation:
Glutathione is a tripeptide found in most tissues, particularly in the liver. It performs important detoxification functions for all cells. The enzyme, glutathione S-transferase conjugates glutathione with drug intermediates to form a drug-glutathione conjugate. This conjugate can easily be excreted through bile or urine.
Amino acid Conjugation:
This is an important reaction in xenobiotic biotransformation; particularly for xenobiotics with carboxylic group or an aromatic hydroxylamine groups. Drug intermediates combine with glycine or glutamine to form an amino acid conjugate.
I think it is B-collection
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Hello!
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❖ Deoxyribose is a sugar that comes from ribose.
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~ ᴄʟᴏᴜᴛᴀɴꜱᴡᴇʀꜱ
Answer: The main reason why only 2 molecules of NADH is formed during glycolysis when it appears that as many as a dozen could be formed is because during glycolysis,most of the free energy that are available from the oxidation of glucose remains in one of the products of glycolysis known as pyruvate which acts like glucose but doesn't undergo metabolism.
Glycolysis is the splitting of sugar molecules into useable/ manageable forms,it can also be seen as the aerobic catabolism of sugar inorder to produce energy in the form of ATP,NADH and PYRUVATE.The following are the products of glycolysis; pyruvate,2 molecules of ATP and 2molecules of NADH.
Pyruvate are used in aerobic respiration or anaerobic respiration if oxygen is not available.
