Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
Answer:
The correct answer is option B. It bind to a receptor in the plasma membrane.
Explanation:
Hormones can be aminoacid based hormones (peptide or amine) or the steroid base hormones on the basis of their nature. Amino acid based proteins are molecules that are proteins,
Peptide hormones are the protein or peptide molecule that release in blood by the exocytosis in the form of preprohormones that mature later and bind to the receptor present on the surface of the plasma membrane of the target cell. The binding of the peptide hormone to the receptors a secondary messenger shows up in the cytoplasm.
Thus, the correct answer is option B. It binds to a receptor in the plasma membrane.
Answer:
If the oil spilled in the gulf would have been processed oil, it would be worse than a normal oil spill as these oils have a higher shelf life.
Explanation:
Oil spills happen when a large quantity of oil gets mixed with large water bodies like <em>sea and oceans</em>. The oil being denser than water floats on the surface and does not mix with the water. It forms a coating on top of the water.
The difference between processed oil and normal oil is that they are heated at very <u>high temperatures</u> and this results in oxidation which creates <em>free radicals</em>, which are not good for the body and its cells. Also they have a very long shelf life due to which they will remain on water for a long time.
When oil spills happen, the <em>wind</em> cause the spill to spread over the water surface, thereby engulfing a large amount of area. The major disadvantages of the spill are:-
- The oil gets stuck in the feathers of the birds who come by to dip themselves,
- Animals like whale, dolphins have blow holes for releasing water. the oil covers these holes and makes it difficult for them to breathe.
- The fur of animals like <u>seal and otter </u>gets mixed with the oil and can prove harmful to them as it gets them exposed to cold.
- The overall BOD of the water body decreases, and organisms which use sun rays coming inside the ocean suffer as these get blocked.
- Since processed oil has longer shelf life, a large quantity of animals will suffer and die.
