Answer:
Forms of passage of substances across the blood–brain barrier. (A) Passive diffusion: fat-soluble substances dissolve in the cell membrane and cross the barrier (e.g., alcohol, nicotine and caffeine). Water-soluble substances such as penicillin have difficulty in getting through.
The answer to you question is the second options.
B) Agility
Maaari silang labis na dosis
If have to want to do it to achieve it