There are a lot of things that could go wrong but the key points are that
1- Technology use, depending on the parts you bring to africa they illiterate so their use of technology will have no technical cause.
2-Internet use. Using technology there will most likely have no power or WIFI as we depend on they would have to use the non-WIFI part of internet which there isn't much to do so this will technically make the technology useless in Africa.
He was referring to the fact that the settlers couldn't farm and that they were rude to the natives who knew how to so Powhatan said the natives couldn't help the settlers anymore. hope that helps :)
Any town that was connected to the rail road were soon abandoned because you couldn't quickly get into our out of the town. everyone moved close to rail road stations
