The answer is fusion of gametes via fertilization.
it was Louis Pasteur(1822-1895) a French chemist first discovered what causes illness hope this helps!
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Rickets develops in growing children who are not exposed to sunlight and have a deficiency of vitamin D, phosphorus or calcium. The disease leads to symptoms such as softening/weakening of the bones, muscle weakness and delayed formation of teeth. The disease is most often observed in young children that are aged between 6 to 24 months of age.