Answer:
1. Weaker
2. Continuous
Explanation:
A tumor suppressor gene codes for retinoblastoma protein (pRb). The retinoblastoma protein binds to transcription factor E2F when DNA damage is detected. The E2F bound to pRb can not stimulate expression of genes that code for proteins required during the process of DNA synthesis. The cell can not enter the S phase.
On the other hand, when the retinoblastoma protein is phosphorylated by cyclin E-CDK2, E2F transcription factor is free to stimulate the expression of genes required for DNA synthesis and the cell proceeds from G1 to S phase.
When the mutated retinoblastoma gene code for a protein that serves as phosphorylated protein, it will not be able to bind strongly with E2F and there would be continuous expression of genes required for S phase.
<span>Well this isn't actually a question but to market to a company like this you first have to impress a small number of people in a single chain of command. Your products don't have to be marketed to a company as a whole or to a single rung of the food chain but to each successive member in a hierarchy in the company. Firstly to the employee, then to their management then to the ones who actually making the decision to buy.</span>
The answer is A, Truth
Hope this helped somehow ^-^
Answer:
Output force is 4.8 N
Explanation:
A pulley is a simple machine made of a grooved wheel with a rope or cable wrapped around it. Pulleys are used in the transmission of energy or motion.
The input force is also known as the applied force while the output force is the force exerted on an object by a simple machine.
The mechanical advantage of a pulley is the ratio of the output force to the input force.
Mechanical advantage = output force / input force
Substituting:
0.48 = output force / 10
Output force = 4.8 N
