*Sickle cell disease is a constitutional corpuscular hemolytic anemia related to an abnormal structure of the globin chain. It is an autosomal recessive disease, which means homozygosity is necessary to fully express the illness.
*It corresponds to the synthesis of an abnormal hemoglobin, HbS, which is different from normal Hb (HbA).
*The S allele (located in the chromosome 11), responsible for the anomaly, is especially widespread in the African continent, it is also found in other regions of the Mediterranean.
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*Mutation GAG to GTG leading to the substitution Glutamine by a valine in position 6 of the chain of the globine.</span>
Wings would be different in human and pigeons.
A negative tropism is when a plant grows away from stimulus
<u>Answer:</u>
<em>Colchicine is also known as mitotic poison. When it is added the separation of chromosomes of daughter cells are stopped. </em>
<u>Explanation:</u>
This is because the formation of spindle fiber is not allowed in the mitosis phase. Basically it is the process of arresting the mitosis at metaphase to study the chromosomes properly.
The addition of colchicine prevents the chromosomes to move to opposite poles. It makes the cell polyploidy. Hence the of addition of colchicine is the polyploidy of the cell.
