I believe the answer is Are the main factor in... hope this helps
Hey!
I believe you are referring to Edgar Allan Poe.
Hope this helps! :)
Answer:
them
Explanation:
pronoun
used as the object of a verb or preposition to refer to two or more people or things previously mentioned or easily identified.
"I bathed the kids and read them stories"
to me N° 4 should be right
hope I helped !