Advantages:
- It brings a unique species
-muktiple offspring that evolve in a fast time
Disadvantages:
-It takes two people
- It takes time
Hope this helps :)
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
<span>The question says, 'during embryonic development, if the anus develop before the mouth, the organism is a ............ The correct option is B. In deuterostome during embryonic development anus develops first from or near embryonic blastopore, mouth develops later at some distance from the blastopore or from the opposite end.</span>
Answer:
Environmental awareness is an incredibly important part of our lives. In order to protect the sustainability of the planet, everyone needs to commit to becoming more environmentally aware. Environmental degradation is detrimental and is jeopardising the long-term health and security of animals, plants and humans.
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