Given our understanding of the mechanisms behind genetic expression, we can confirm that when comparing skin cells to kidney cells, the only correct option is option 4 which states that the cells "<u><em>transcribe many different genes</em></u>".
The human genome encodes for <em><u>every gene in the human body</u></em>. This genome sequence is stored in the chromosomes of cells. These chromosomes are identical for every single cell in the human body. Therefore, every cell contains the same DNA, genes, and transcription factors in its chromosomes.
What allows each cell type in the human body the ability to differentiate from one another and complete vastly different functions is the way in which these genes are expressed. Though every cell contains the entire genetic code, only some genes for each cell are transcribed, which results in a different combination of proteins in each cell and leads to the difference between skin and kidney cells (as just one of many examples).
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