Answer:
1.reduced oxygen levels
4.blocked blood vessels
3.heart disease
Explanation:
Sickle cell anemia is a disease that causes changes in the shape of red blood cells. These globules are responsible for the oxygenation of tissues, when a person has sickle cell anemia, these globules have an incorrect structure, lose their rounded and elastic shape, assume a plump appearance and become hardened. This prevents the red blood cells from being able to couple with the oxygen molecules.
As a result of this, people like this disease have problems such as: blockage of blood flow and lack of oxygenation in the tissues, joint pain, intense fatigue, pallor, delayed growth, wounds, gallstones, neurological, cardiovascular, pulmonary and kidney problems.
