The toxic condition characterized by retention of
nitrogenous substances in the blood is called uremia. Uremia is a toxic condition caused by
retention in the blood of nitrogenous waste products normally excreted in the
urine. Acute renal failure denotes a
sudden onset of renal failure, such as that caused by an accident, certain
drugs or poison. The kidneys may recover or the damage may be permanent. If the
kidneys stop functioning this condition is what they called uremia, therefore
the body is full of extra water and
waste products, leading to swelling in the hands or feet, fatigue and weakness.
End-stage renal disease refers to when the kidneys have lost all or nearly all
function.
