Answer:
As the cells run out of oxygen they switch to anaerobic respiration, which allows the cell to make small amounts of ATP in the absence of oxygen.
Explanation:
The fatigue in the muscle is due to lactic acid fermentation which occurs during vigorous muscular activity when blood is unable to supply enough oxygen to muscles. The lactic acid accumulates in the muscle causing pain and muscle cramps.
Glucose → Lactic acid + 2ATP
When the terminal (third) phosphate is cut loose, ATP becomes ADP (Adenosine diphosphate; di= two), and the stored energy is released for some biological process to utilize.
Its the first one, the second one and the fourth one! I hope this helps