Answer:
They were affected personally, culturally and materially among other ways.
Explanation:
The European colonization of the American continent affected the American Indians very strongly.
The first way they were affected had to do with their health. Due to the historical isolation of the European and American continents from each other, the American Indians had no defenses against the viruses and bacteria that the Europeans brought with them, such as smallpox for example.
These viruses and bacteria were the main killers of almost 70 million Native Americans across the continent in just 100 years of conquest and colonization.
Second, they were affected by the elimination and prohibition of further developing their cultural values and principles. Like their religion, the form of family and social organization, ways of feeding and healing, among other cultural features that were devastated by the conquest and colonization.
Third, his material world was also very affected. Their lands, their cities (in the case of the more advanced tribes), their natural resources and sacred places, were violated by the new European dynamic of occupation and exploitation of the colonized territories.
Among others, these are the ways in which the Indians of the American continent were affected by the conquest and colonization of their territories, people and cultures.