1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Solnce55 [7]
3 years ago
10

Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes

Biology
1 answer:
MrMuchimi3 years ago
8 0
<span>Canagliflozin is a recently discovered drug that is used in the treatment of type 2 diabetes, by inhibiting SGLT2 transporters in kidneys that reabsorb glucose from the urine.
EFFICACY:
Cohort studies were made to compare canagliflozin to other molecules (glimepiride and sitagliptin) by evaluating the life quality, weight and </span>HbA1c (glycated hemoglobin) for 52 weeks. it was found that canagliflozin has a better efficacity and a better effective cost ratio.

SIDE EFFECTS:
The most frequent side effects are constipation, thirstiness, nausea, and headache.
Due to its mechanism of action, a high glucosuria can be found also.
Severe complications can occur, like euglycemic ketoacidosis. This drug has a high amputation and risk (like other SGLT2 inhibitors) and a high fracture risk (due to the diminution of the mineralization of the bones).

You might be interested in
Match each type of organism to a characteristic that describes it. Produce food from inorganic materials cannot survive in the p
TEA [102]
<h2>Type of Organisam to a Characteristic </h2>

The chloroplast produces food from inorganic materials. Anaerobic organelles cannot survive in the presence of oxygen this is because oxygen does not help in it's growth. Though eukaryotic cells contain cell nucleus. This is why chloroplasts produce food through photosynthesis.  

7 0
4 years ago
The regularity of basic functions such as hunger, excretion, sleep, and wakefulness is known as __________.
Degger [83]
The regularity of basic functions such as hunger, excretion, sleep, and wakefulness is known as <span>dimensions of temperament; rhythmicity.</span>
8 0
3 years ago
A biologist studying a desert ecosystem observes that the population of a lizard species increases following a particularly hot,
bekas [8.4K]
Based on the description of events, being that the lizard population appears to increase as soon as the snake population decreases, it appears that the snakes prey on the lizards. This suggests that the snake is a keystone species. A keystone species is one that has a dramatic effect on maintaining the balance of an ecosystem. As soon as the snake population decreases, major changes occur to the ecosystem, such as the lizard population increasing.

Therefore, the answer is D: <span>The snake is a keystone species in the ecosystem.</span>
3 0
4 years ago
Read 2 more answers
What is the function of these organelles? endoplasmic reticulum: Golgi body: mitochondrion: ribosome:
liraira [26]

Answer:

Endoplasmic Reticulum: help form and store proteins.

Golgi Body: sorting and processing proteins.

Mitochondria: converts food (or protein) into energy.

Ribosome: synthesize proteins for use throughout the cell.

Hope this helps

-Amelia

7 0
3 years ago
Read 3 more answers
Please help me asap it should go in 5mins​
Olenka [21]

Answer:

loam

i am not 100% sure but logically it's loam

3 0
3 years ago
Other questions:
  • What is the theoretical probability of rolling an odd number on a fair die with six faces?
    9·1 answer
  • Why is it important 2 protect the world's reef system? Do u think artifacts reefs r the solution? Explain your answer.
    15·1 answer
  • What would most likely happen if an ecosystem that regularly recieved sunlight no longer received sunlight?
    13·1 answer
  • 1. Nitrogen from the atmosphere must be converted into what molecule? What organisms add this molecule to the soil? ​
    8·1 answer
  • What do you think is an advantage of a close circulatory system?
    10·1 answer
  • Which of the following is not a reason plants need to consume water
    15·2 answers
  • Which of the following organic molecules is a major storage carbohydrates used to store energy in plants ?
    5·2 answers
  • How does independent assortment affect genetic diversity?
    15·1 answer
  • Which statement is true?
    13·1 answer
  • Which action best demonstrates the transformation of mechanical energy to heat energy and sound energy? (10 points)
    11·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!