Answer:
The correct answer is option d.
Explanation:
The production of Acetyl-CoA takes place by the dissociation of both carbohydrates and lipids in the process of glycolysis and beta-oxidation. It then moves into the TCA cycle in the mitochondria and combines with oxaloacetate to give rise to citrate.
In the given case, no labeling will be found in the acetyl-CoA. The labeled C3 and C4 carbon of glucose signify the carboxyl carbon of pyruvate. In the succeeding reactions of the transformation of pyruvate to acetyl-CoA, the carboxyl carbon gets lost in the form of carbon dioxide. Thus, acetyl-CoA does not comprise any labeled C3 and C4 of glucose.
Gulliver
was a surgeon and he was on the ship named “Antelope”. When a violent storm
came and the ship sank, all the crew members were engulfed in the ocean. Gulliver
somehow managed and swam to the shore.
He
was so tired that soon he fell into a deep sleep and when he woke he saw that
he was caught and chained by little men called Lilliputians who lived there.
At
first, when he tried to free himself, they were frightened of him and fire
dozens of arrows in to his chest, hands, and arms but later they treated him
very well. Gulliver admitted that first he want that take people in his hand
and crush them but when they treated him well, he also treated them well. He was
impressed by their nice hospitality they showed.
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B. Style
A writers choice of words, or diction, mostly affects an essay’s style.
Answer and Explanation:
The Huntington disease is caused by a mutation in the gene that codifies for the Huntingtin protein (Htt). The mutation produces an altered form of the protein leading to the neuron´s death in certain areas of the brain.
The Huntington disease characterizes for being,
- Hereditary, passing from generation to generation. To express the disease, a person must have been born with an altered gene.
- Autosomal, affecting men and women equally, because the mutated gene is located on an autosomal chromosome.
- Dominant, which means that by getting only one copy of the altered gene coming from any of the parents, the receiving person will express the disease. The mutation in the gene dominates over the normal gene copy.
- Expressed by heterozygosis. Most people affected by the disease are heterozygous, with a normal copy and a mutated copy.
There are just a few cases all around the world (3% approximately) in which the disease is expressed with no family history. The progenitors are not affected by the mutation. These cases are very rare and are called <u>"de-novo" mutations.</u> A new mutation is spontaneously produced and it is not inherited from any of the parentals. It consists of an increase in the number of CAG repetitions. In a normal person, the number of CAG repetitions is less than 35. When there are 40 or more repetitions it occurs the disease. But when there are between 35 and 39 repetitions, the penetrance of the disease is incomplete. This is a "gray zone". Those alleles that fall in the gray zone are unstable and might produce the HD. Individuals with these unstable alleles have a tendency to increase the number of repetitions from generation to generation until the number reaches 40 repetitions and the person expresses the disease. This <u>usually occurs in the paternal germinal line</u>, as it is particularly unstable in sperm and probably meiosis greatly affects their instability, causing an increase in the number of CAG repeats.
