Adaptations are
the result of evolution in different living organisms. This process occurs amazingly
through gene mutation but it takes a very long period in time. Adaptation
processes occur to help species survive and thrive in the ecological balance of
life. Structural adaptations are physical features of an organism that adapted
through time. An example of this are the bills of a bird and the fur of bears
that they generally need for their survival; birds for hunting, and bears to
protect them from low climate areas.
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Functional or
Behavioral adaptations refer to particular things that an organism or organisms
do to survive. In the example above, behavioral adaptations that birds do is
through certain bird calls and migration, while bears hunt during warmer
seasons and hibernate during winter season. </span>
<span>Beneficence commonly is referred to as "doing of good"; it is related to the nurse's duty to help clients further their legitimate interest within the boundaries of safety. Unfortunately in this situation the client's priority is relief from pain and the nurse should be working with other health team members to achieve this objective. Veracity is defined as telling the truth. Autonomy, as an ethical principle, means that the nurse respects the client and the choices that are made. Paternalism occurs if the nurse interferes with the individual's autonomy by disregarding the client's choices.</span>
Regulation of HMG-CoA reductase is termed as the rate of controlling enzyme of the mevalonate pathway which produces other isoprenoid and cholesterol.
The regulation of cholesterol is done by regulating the rate which determines step catalyzed by HGM -CoA reductase.
There is long-term and short-term regulation where HGM-CoA is inhibited by phosphorylation and catalyzed of proteins. There is regulated proteolysis of HGM-CoA reductase where degradation of HMG-CoA reductase by oxidized derivatives of cholesterol.
