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Nitella [24]
3 years ago
12

How does a cell handle misfolded proteins

Biology
1 answer:
ANEK [815]3 years ago
5 0
<span>Cells primarily recognize exposed hydrophobic patches when identifying misfolded proteins. This is very prevalent in bacteria and I would assume that similar mechanisms are used in eukaryotes. There is also a system where misfolded proteins are tagged by different glycosylation patterns, but I don't remember much about that part.</span>
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An individual with Huntington disease has two normal parents. What are plausible explanations for this pattern of inheritance? C
Vitek1552 [10]

Answer and Explanation:

The Huntington disease is caused by a mutation in the gene that codifies for the Huntingtin protein (Htt). The mutation produces an altered form of the protein leading to the neuron´s death in certain areas of the brain.

The Huntington disease characterizes for being,

  • Hereditary, passing from generation to generation. To express the disease, a person must have been born with an altered gene.
  • Autosomal, affecting men and women equally, because the mutated gene is located on an autosomal chromosome.
  • Dominant, which means that by getting only one copy of the altered gene coming from any of the parents, the receiving person will express the disease. The mutation in the gene dominates over the normal gene copy.
  • Expressed by heterozygosis. Most people affected by the disease are heterozygous, with a normal copy and a mutated copy.

There are just a few cases all around the world (3% approximately) in which the disease is expressed with no family history. The progenitors are not affected by the mutation. These cases are very rare and are called <u>"de-novo" mutations.</u> A new mutation is spontaneously produced and it is not inherited from any of the parentals. It consists of an increase in the number of CAG repetitions. In a normal person, the number of CAG repetitions is less than 35. When there are 40 or more repetitions it occurs the disease. But when there are between 35 and 39 repetitions, the penetrance of the disease is incomplete. This is a "gray zone". Those alleles that fall in the gray zone are unstable and might produce the HD. Individuals with these unstable alleles have a tendency to increase the number of repetitions from generation to generation until the number reaches 40 repetitions and the person expresses the disease. This <u>usually occurs in the paternal germinal line</u>, as it is particularly unstable in sperm and probably meiosis greatly affects their instability, causing an increase in the number of CAG repeats.

6 0
3 years ago
What is a releaser? In biology
coldgirl [10]

Answer:

A releaser is a stimulus from one animal to another, which causes a particular response.

Explanation:

google

6 0
3 years ago
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Explain why carbon monoxide is or is not an atom.​
Alexxx [7]

Answer: carbon monoxide is one carbon atom and one oxygen atom

Explanation:

7 0
2 years ago
Chloroplasts and mitochondria are both involved in energy conversion in cells. Select the other similarity they share. Question
Afina-wow [57]

Chloroplasts and mitochondria are similar in the sense that they both contain DNA.

MITOCHONDRIA AND CHLOROPLAST:

  • Mitochondria is a membrane bound organelle found in eukaryotic cells. Mitochondria is the energy production site of cells because it is where cellular respiration takes place.

  • Chloroplast is another membrane-bound organelle in eukaryotic cells. They are the site of photosynthesis in plants.

  • Mitochondria and chloroplast are both involved in energy conversion in cells because electron transport chain occurs in both organelles.

  • However, another similarity between these two organelles is that they contain extra-chromosomal DNA.

Learn more about organelles: brainly.com/question/21759042?referrer=searchResults

3 0
2 years ago
Fossils are only found in
insens350 [35]

Answer:

sedimentary rock

Explanation:

fossils are most commonly found in sedimentary rock. Unlike most igneous and metamorphic rocks, sedimentary rocks form at temperatures and pressures that do not destroy fossil remnants. Often these fossils may only be visible under magnification.

3 0
3 years ago
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