Traits that are passed down on an X or a Y chromosome are sex-linked traits. Most of the time males are affected by sex-linked traits because males only have one X and a Y. The Y is the chromosome that makes a man, a man.
I don’t think it would change the effectiveness , if bees got used to it or it had always been like that, they wouldn’t have a problem, but if it was a sudden change then they might dislike it