The wording to this question is a little confusing. detrimental well being since detrimental means to causing harm. But i believe that you mean what are two factors to a well being in a relationship. In that case: 1. good communication, that is very important in all types of relationships. 2. would be trust, and the ability to relay on the other for support and vice versa
The context suggests a noun that means "medicine", i.e. a pill or a liquid used in treating illness. The correct choice would be C. medication because that's what the term 'medication' means: drugs used to treat an illness.