<h3><u>Answer;</u></h3>
When an area is holoendemic, the HbS allele frequency is between 0.52 and 4.04.
<h3><u>Explanation;</u></h3>
- <em><u>HbS allele is the sickle cell hemoglobin allele that provides immunity to malaria. This is because people with the sickle cell allele have a selective advantage in areas where there is a high incidence of malaria.</u></em>
- Therefore, natural selection will favor the population with HbS allele in a Malaria holoendemic (most individuals are infected) region. The HbS allele frequency in this population is expected to be high.
- After malaria is cured, the frequency of the HbS allele should decrease in regions with a lot of mosquitoes because having one copy of the HbS allele will no longer be advantageous in these regions.
The correct answer is option <u>D. Its absence would affect many organism present in the community. </u>
