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Alinara [238K]
3 years ago
6

Why are genomes important to the development of vaccines

Medicine
2 answers:
Effectus [21]3 years ago
6 0
Exome sequencing provides a cost-effective alternative to whole genome sequencing, as it targets only the protein coding region of the human genome responsible for a majority of known disease-related variants. Whether you are conducting studies in rare mendelian disorders, complex disease, cancer research, or human population studies, Novogene’s comprehensive human whole exome sequencing (hWES) service provides a high-quality, affordable, and convenient solution.
Cerrena [4.2K]3 years ago
4 0
Vaccines are the most efficacious means of minimizing the impact of infectious diseases on the human population. The challenges and importance of making vaccines that will meet FDA approval have never been greater. Genomics has the potential to improve the process of vaccine development substantially. Genome sequencing can help to identify genetic patterns related to the virulence of a disease, as well as genetic factors that contribute to immunity or successful vaccine response. All this information could lead to vaccines with better and more specific targets that elicit more successful protective immune responses. Comparing the genome sequences of viruses that cause infection with those that do not may provide additional insights. In turn, genome manipulation can facilitate derivation of attenuated strains or other vehicles for delivery of the desired antigens to stimulate immune response. On the other end of the spectrum, analysis of host diversity can reveal effective immune responses and possibly the genetic basis for inappropriate response. The recent progress in definition of the innate immune system, necessary for acquired response, should facilitate the definition of this host diversity.
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The mechanism under the therapeutio effect of lovastatin is:
Ilya [14]

Answer:

(B). inhibiting HMG-CoA reductase.

Explanation:

Lovastatin is a drug, which is used to reduce risk for cardiovascular diseases and to reduce level of cholesterol in blood.

It works by inhibiting HMG-CoA reductase (3-hydroxy-3-methylglutaryl-coenzyme A reductase) enzyme, required for the formation of mevalonate from HMG-CoA.

Mevalonate is building block for the biosynthesis of cholesterol. Hence, lovastatin inhibits cholesterol production by inhibiting synthesis of mevalonate.

Thus, the correct answer is option (B).

 

7 0
3 years ago
One of the core symptoms of post-traumatic stress disorder (PTSD) is intrusive memory: disturbing, unwanted memories of the trau
SpyIntel [72]

Answer:

The onset, and treatment of PTSD is no easy matter. In order for such a disorder to appear, which is later expressed with tremendous peaks of stress, crisis, behavioral problems, panic disorders, anxiety disorders, and many more debilitating conditions, a person must have experienced an event, or circumstance, that traumatically negatively impacted the correct psychological and emotional processes of the mind. In these patients, one the most common situations is that panic attacks and anxiety peaks happen particularly when the traumatic event, moment, or circumstance is remembered, and they are very good at remembering not just the moment itself, but all elements that surrounded that trauma. Also, they are able to make really clear connections and associations between those events and normal events in life that, when they appear, trigger the defensive responses of the mind.

The idea of administering a patient with PTSD with medication that would stop memory formation shortly after a traumatic event would not be a good idea simply because while the drugs focus on the chemical processes involved in memory formation, this procedure ignores that memory is much more than just chemicals in the brain. This has been show time and time again in research. Even with strong medication that basically generates amnesia, or trauma to the brain that may cause amnesia, it has been seen, and science cannot yet fully explain how, these patients may have partial, or total recovery of memories. And because the process of memory formation is still so misunderstood, and not all the factors involved are completely known, simply administering a drug that would stop the hormones that are believed to play a role in memory formation could become more of a problem for the patient. Also it is not being considered that amnesia causes even more stress in patients, as somehow the brain still recognizes that there is information present, but cannot simply bring it to concious awareness.

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3 years ago
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Vipassana and Samatha
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Which is the most important prerequisite for measuring health care quality delivered in the hospital
Andrei [34K]

The most important prerequisite for assessing the quality of health care delivery system is to collect the medical records of the patients admitted and discharged from the hospital.

Change it up a bit <3

4 0
2 years ago
What's the most common use of computers in the pharmacy ?
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A. Hhdhhjfjfjjfjfjjf
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