Explanation: In Act V, Scene I, of "The Tragedy of Macbeth", by William Lady Macbeth's guilt causes her a great <u><em>perturbation</em></u> of spirit. A doctor is summoned to visit Lady Macbeth. She has began to sleepwalk and sees blood in her hands. There is no blood in her hands but in her perturbation she tries to wash them.
It’s because the pronunciation is technically a ‘y’ sound, and even though y is sometimes considered a vowel, ‘an’ is not used in front of words that start with the ‘y’ sound.