Is there more information?
The most simple answer I can think of would be that improper handling can cause damage to the test subject, which would effect the results, making them unreliable.
Answer:
C) Faults form in the lithosphere.
Explanation:
Faults form in lithosphere is part of transform boundaries because the plates simply slide past each other without causing any change to the lithosphere (i.e it is neither created nor destroyed) which is why transform boundaries are also sometimes referenced when we speak about phenomena related to when plates slide in opposite directions.
Answer:
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