Problems with native Americans and the Mexican people. <span />
He made several trips to North and South America in 1492<span>, </span>1493,1498 and 1502.In 1492 landed in the <span> Caribbean but mistook it for India, where he had wanted to sail. He also went to many islands in the West Indies. In 1493 and 1498 discovered South America and explored many of the islands and coasts there. He explored much of the Caribbean in his life.</span>
I think b makes the most sense. The press would have most likely helped many Protestants share their works easier, such as Martin Luther with the 95 theses.
The Missouri Compromise, which preserved the balance between Free and Slave states.