Question

The researcher had hypothesized that the addition of the vitamin that is similar in structure to NADH would increase the activity of the mutated NADH dehydrogenase enzyme in individuals with the disorder. Explain how the vitamin most likely increased the activity of the enzyme

Answer 1

Answer:

It is expected that the mutation helps the enzyme to bind to the vitamin, and this interaction may be necessary to maintain the activated state of the enzyme.

Explanation:

The NADH dehydrogenase converts nicotinamide adenine dinucleotide (NAD) from its reduced form (NADH) to the oxidized NAD+, thereby this enzyme is required for generating ATP by electron transport.